Recently, Professor Piaoping YANG's team from the College of Materials Science and Chemical Engineering successfully developed nanomedicine in a nanorod-shaped structure using intermetallic compounds. For the first time, they employed this drug for the synergistic treatment of tumor pyroptosis and disulfidptosis. This study provides a theoretical foundation for the advanced development of highly efficient nanomaterials and cancer therapies, offering advantages of high therapeutic efficacy and low toxicity. The research findings were published in the Nature sub-journal Nature Communications, under the title "Intermetallics Triggering Pyroptosis and Disulfidptosis in Cancer Cells Promote Anti-Tumor Immunity."

Nanocatalytic medicine holds great promise for tumor treatment; however, the efficiency and specificity of catalysis currently pose significant challenges to its further development. Precisely regulating nanostructures to achieve maximum catalytic effect is essential for effective tumor treatment.

A schematic illustration of the synthesis of nanocomposites and the synergistic therapy process is included.

Original link: https://www.nature.com/articles/s41467-024-53135-2