A research team led by Professors YANG Piaoping and GAI Shili from the College of Materials Science and Chemical Engineering has achieved a significant breakthrough in the interdisciplinary field of nanocatalytic medicine and advanced functional materials. The team proposed a novel “defect-interface synergistic functionalization” strategy, successfully activating the potential of natural superlattice materials to achieve a synergistic enhancement of photothermal, thermoelectric, and enzyme-catalytic effects for tumor therapy. Experimental results indicate that this nanoplatform achieves a tumor inhibition rate of up to 94% with excellent biosafety, opening new avenues for the development of non-invasive and precise tumor treatment technologies.

The study, titled “Defect-Interface Synergistic Functionalized BiCuSeO-Ag Superlattice Nanoheterojunctions for Photothermal-Thermoelectric-Enzyme Co-Catalytic Tumor Therapy,” has been published in Matter, a leading international journal in the field of materials science. Harbin Engineering University is the primary affiliation for this research. ZANG Pengyu, a doctoral student from the College of Materials Science and Chemical Engineering, is the first author, with Professors YANG Piaoping and GAI Shili serving as corresponding authors.

Mechanisms of Enhanced Thermoelectric Performance, Carrier Transport, and Antitumor Activity

Launched in 2020, Matter has an impact factor of 17.5 and is one of the flagship journals published by Cell Press, focusing on materials science and interdisciplinary research. It is a sister journal to Cell, Chem, and others. The journal is dedicated to publishing high-impact, groundbreaking research in frontier interdisciplinary fields such as materials science, energy, nanotechnology, and biomedicine, and it enjoys significant influence and high recognition within the international academic community.

Original article link: https://www.sciencedirect.com/science/article/pii/S2590238526001256?dgcid=author