A team led by Professor YANG Piaoping from the College of Materials Science and Chemical Engineering has recently achieved a significant advance in the field of nanocatalytic medicine. They have proposed a novel mechanism—“maintaining hot electrons via non uniform strain modulated phonon scattering”—that simultaneously preserves hot electron energy and enhances enzyme catalytic efficiency. This work provides a new theoretical foundation and technical pathway for highly effective tumor therapy.

The results were published under the title “Maintaining Hot Electrons via Non Uniform Strain Modulated Phonon Scattering for Enhanced Enzyme Therapy” in Angewandte Chemie International Edition, a leading international journal. Harbin Engineering University is the primary affiliation for the paper. CAO Sida, a Ph.D. student from the college, is the first author, while Professors GAI Shili, HE Fei, and YANG Piaoping serve as corresponding authors.

Schematic illustration of the preparation process for PWO nanobelts used in enzyme therapy and the mechanism of non uniform strain modulated phonon scattering

Angewandte Chemie International Edition is one of the most influential academic journals in the field of chemistry worldwide. Published by the German Chemical Society, it has long been dedicated to publishing original, pioneering research in chemistry and related interdisciplinary fields, and enjoys an outstanding reputation in the global academic community.

Link to the paper:

https://onlinelibrary.wiley.com/doi/10.1002/ange.4271452